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. 2021 Jan 11;14:618422. doi: 10.3389/fnins.2020.618422

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Copyright © 2021 Kovács, Brunner, D’Agostino and Ari.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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KEMCT-evoked changes in blood R-βHB and glucose levels in female and male WAG/Rij rats. KEMCT administration (gavage, 2.5 g/kg, once per month) significantly elevated the blood R-βHB levels (A,B) and decreased blood glucose levels (C,D) compared with the control in both female and male rats. R-βHB, R-beta-hydroxybutyrate; KEMCT, mix of ketone ester (KE) and medium-chain triglyceride (MCT) oil in a 1:1 ratio. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.