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Technologies to study functional genomics of AMD. Genome-wide analysis methods (GWAS, eQTL, TWAS, and eCAVIAR) can be used to identify candidate genes linked to AMD. Expression of these genes in the retina can be mapped using transcriptomic technologies. Functional study of AMD-associated genes can be facilitated using in vitro AMD models and molecular tools. scRNA-seq, single cell RNA sequencing; snRNA-seq, single nuclei RNA sequencing.
