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. 2021 Jan 11;8:619079. doi: 10.3389/fcell.2020.619079

FIGURE 4.

FIGURE 4

Loss of Aerrie and YBX1/2/3 result in impaired sprouting. (A,B) HUVECs were treated with gapmeR (gap) targeting Aerrie, siRNA (si) targeting YBX1/2/3 or a respective control. (A) Sprouting assay (B) Quantification of the continuous and discontinuous sprouts per condition. (n = 3, at least 10 spheroids per experiment). Sprouts measured by the distance from the tip cell to the stalk cell. **p < 0.01; ****p < 0.0001; ns, not statistically significant.