Table 1.
Changes in Transgender Men and Women on Sex Hormone Therapy.
| Study | Population | Duration | Prehormone therapy serum creatinine | Posthormone therapy serum creatinine |
P value (between group*) (pre/post**) |
|---|---|---|---|---|---|
| Ruestche89 | 24 transwomen 15 transmen |
12.5 y 7.6 y |
Not applicable Not applicable |
80 µmol/L (10) 90 µmol/L (6) |
Not reported |
| Lapauw90 | 23 transwomen 46 age, height Matched cismales |
>3 y | Not applicable Not applicable |
0.78 mg/dL ± 0.11 (69 µmol/L ± 10) 0.94 mg/dL ± 0.12 (83 µmol/L ± 11) |
P < .001* |
| Wierckx91 | 50 transmen 50 transwomen |
6.3 y 8.7 y |
Not applicable Not applicable |
0.9 mg/dL (0.9-1.0) (80 µmol/L) 0.8 mg/dL (0.7-0.9) (71 µmol/L) |
P < .001* |
| Sorelle85 | 133 transwomen 89 transmen |
>6 mo | 0.98 mg/dL (87 µmol/L) 0.74 mg/dL (65 µmol/L) |
0.86 mg/dL (76 µmol/L) 0.90 mg/dL (80 µmol/L) |
P < .0001** P < .0001** |
| Fernandez92 | 33 transwomen 19 transmen |
18 mo | 0.90 mg/dL (0.03) (80 µmol/L [3]) 0.73 mg/dL (0.03) (65 µmol/L [3]) |
0.83 mg/dL (0.03) (73 µmol/L [3]) 0.82 mg/dL (0.04) (73 µmol/L [4]) |
Not reported |
| Jarin93 | 72 transmen 44 transwomen |
6 mo | Not reported | Not reported | P > .05 |
| Scharff86 | 249 transwomen 278 transmen |
12 mo | 78.5 µmol/L (10.8) 66.0 µmol/L (9.0) |
73.1 µmol/L (10.6) 77.4 µmol/L (10.6) |
−5.0 (95% CI: −6.2 to −3.8)** 11.1 (95% CI: 10.1 to 12.2)** |
| Wierckx94 | 53 transmen 53 transwomen |
1 y | 0.74 mg/dL (0.1) (65 µmol/L [9]) 0.9 mg/dL (0.1) (80 µmol/L [9]) |
0.84 mg/dL (0.1) (74 µmol/L [9]) 0.8 mg/dL (0.1) (71 µmol/L [9]) |
P < .001** P < .001** |
| van Kesteren95 | 20 transwomen 19 transmen |
1 y | 81 µmol/L (7) 72 µmol/L (8) |
77 µmol/L (7) 79 µmol/L (9) |
P = .048** P < .001** |
Note. CI = confidence interval.