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The roles of CypA in the lifecycle of influenza A virus. ①E3 ubiquitin ligase AIP4 can accelerate ubiquitin proteasome-mediated degradation of M1. ②By disrupting the interaction between M1 and the AIP4, CypA inhibits AIP4-mediated M1 ubiquitination. ③CypA inhibits the nuclear export of M1.④CypA promotes the production of type I IFN by triggering the RIG-I-mediated signaling pathway
