Table 4.

Binding energies of Ligands docked against Mpro, Plp, RdRp, helicase, and NendoU of SARS-Cov-2

S. No.	Ligands	Binding affinity (kcal/mol)
		NSP5/MPro	NSP3/PLp	NSP12/RdRp	NSP13/Helicase	NSP15/NendoU
1.	4-O-(6-Galloylglucoside)	−7.8	−6.8	−8.9	−9.1	−7.5
2.	Epigallocatechin-gallate	−7.7	−5.9	−8.5	−8.5	−6.9
3.	3-O-(6-Galloylglucoside)	−8.4	−6.6	− 8.4	− 9.0	− 6.8
4.	Epicatechin-gallate	− 8.4	− 6.1	− 8.3	− 8.4	− 7.2
5.	3-Glucogallic-acid	− 6.7	− 5.6	− 7.1	− 7.9	− 7.0
6.	Epicatechin	− 7.1	−6.0	− 7.1	− 7.6	− 6.8
7.	Epigallocatechin	− 6.9	− 5.7	− 7.1	-7.3	− 6.7
8.	3-O-Methyl-gallic-acid	−5.4	−4.8	− 6.2	− 6.1	− 5.2
9.	Gallic-acid	− 5.6	−4.6	− 5.9	− 5.9	−5.0
10.	3-O-Dodecanoyl(3-lauroylgallic-acid)	−5.3	−4.5	−5.8	− 6.4	− 5.7
11.	Lauryl-gallate	− 5.4	−4.1	− 5.5	− 6.1	−5.5
12.	Octyl gallate	−5.8	−5.0	− 5.1	− 6.6	−5.7
13.	4-o-Methylgallic-acid	−5.1	−4.6	−5.0	− 6.0	− 5.1
Control drugs
14.	Dexamethasone	−6.8	−6.4	−7.5	− 8.0	− 7.1
15.	Remdesivir	−7.9	−6.5	− 7.3	− 7.4	− 6.7
16.	Hydroxychloroquine	− 6.3	−5.0	−6.1	− 6.8	− 5.8