Figure 8.

Confocal images of β1-integrin (in green) distribution in MCF-7 cultured in normal gravity (A) and microgravity conditions (B,C) for 24 h. β1-integrin in MCF-7 cells appears localized on the cell membrane both in the on-ground condition and in RPM-cultured cells. β1-integrin shows an increased deposition in RPM-AD (B) when compared to control cells cultured on ground. In the RPM-CLUMP cluster, β1-integrin is almost completely absent (C). Nuclei (in blue) were stained with TO-PRO-3 iodide. Scale bars 20 µm.