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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Recognition of tumor cells by monoclonal antibodies (mAbs). Therapeutic mAbs can recognize tumor antigens and oncogenic peptide/MHC class I complexes on malignant cells. Receptor/IgG fusion proteins, such as NKG2D/Fc, target tumor-associated ligands MICA or MICB.