Table 1.
Characteristics.
| Variables | Total (n = 547) |
Low CaScore (n = 365) |
High CaScore (n = 182) |
p-Value |
|---|---|---|---|---|
| Patient | ||||
| Male gender, n (%) a | 336 (61.4) | 205 (56.2) | 131 (72.0) | <0.001 b |
| Age, years c | 60 (51, 68) | 55 (47, 64) | 66 (60, 71) | <0.001 d |
| Diabetes mellitus, n (%) a | 173 (31.6) | 117 (32.1) | 56 (30.8) | 0.836 b |
| Body Mass Index, kg/m2 b | 26.8 (4.7) | 26.9 (4.9) | 26.7 (4.1) | 0.670 c |
| Smoker, n (%) a | 0.004 b | |||
| Non | 154 (28.2) | 119 (32.6) | 35 (19.2) | |
| Former | 332 (60.7) | 206 (56.4) | 126 (69.2) | |
| Current | 61 (11.2) | 40 (11.0) | 21 (11.5) | |
| Hypercholesterolemia, n (%) a | 153 (28.0) | 96 (26.3) | 57 (31.3) | 0.258 b |
| Total cholesterol, mmol/L | 4.7 (1.3) | 4.8 (1.5) | 4.5 (1.2) | 0.031 c |
| Systolic blood pressure, mmHg | 145 (22) | 143 (21) | 148 (24) | 0.014 c |
| Use of antihypertensive medication, n (%) | 439 (80.3) | 282 (77.3) | 157 (86.3) | 0.017 b |
| Type of dialysis, n (%) a | 0.109 b | |||
| Pre-emptive | 197 (36.0) | 142 (38.9) | 55 (30.2) | |
| Haemodialysis | 250 (45.7) | 162 (44.4) | 88 (48.4) | |
| Peritoneal dialysis | 100 (18.3) | 61 (16.7) | 39 (21.4) | |
| Dialysis vintage, months c | 12 (0, 28) | 11 (0, 25) | 16 (0, 33) | 0.012 d |
| Previous transplants, n (%) a | 0.872 b | |||
| Non | 514 (94.0) | 343 (94.0) | 171 (94.0) | |
| One | 22 (4.0) | 14 (3.8) | 8 (4.4) | |
| Two | 11 (2.0) | 8 (2.2) | 3 (1.6) | |
| Aorto-iliac CaScore, HU | 2994 (294, 7888) | 856 (46, 2994) | 9732 (7918, 14315) | <0.001 d |
| Transplantation | ||||
| Type of donation, n (%) a | 0.025 b | |||
| Living-donation | 301 (55.0) | 215 (58.9) | 86 (47.3) | |
| Donation after circulatory death | 128 (23.4) | 75 (20.5) | 53 (29.1) | |
| Donation after brain death | 118 (21.6) | 75 (20.5) | 43 (23.6) | |
| Male gender donor, n (%) | 253 (46.3) | 160 (43.8) | 93 (51.1) | 0.130 b |
| Donor age, years | 54 (14) | 52 (14) | 59 (12) | <0.001 c |
| No. of HLA-mismatches, n | 3.5 (1.5) | 3.4 (1.5) | 3.6 (1.4) | 0.127 c |
| Warm ischemia time, minutes | 42 (36) | 42 (44) | 41 (13) | 0.676 c |
| Cold ischemia time, minutes | 433 (340) | 415(343) | 470 (331) | 0.076 c |
| Follow-up e | ||||
| eGFR at six-months a | 50 (18) | 51 (19) | 46 (17) | 0.004 c |
| eGFR at one-year a | 51 (21) | 53 (20) | 48 (21) | 0.007 c |
| Haemoglobin at one-year, mmol/L | 8.3 (3.8) | 8.3 (4.6) | 8.2 (1.1) | 0.811 c |
| Calcium at one-year, mmol/L | 2.43 (0.14) | 2.43 (0.14) | 2.45 (0.14) | 0.034 c |
| Phosphate at one year, mmol/L | 0.93 (0.21) | 0.95 (0.21) | 0.89 (0.19) | 0.004 c |
| Albumin at one-year, g/L | 43 (3) | 43 (3) | 43 (3) | 0.234 c |
| Glucose at one-year, mmol/L | 5.9 (5.1, 7.3) | 5.7 (5.1, 7.2) | 6.2 (5.4, 7.6) | 0.005 d |
| PTH at one-year, pmol/L | 10 (7, 16) | 10 (7, 15) | 12 (8, 16) | 0.064 d |
| Protein excretion at one-year, g/24 h | 0.2 (0.1, 0.3) | 0.1 (0.1, 0.2) | 0.2 (0.1, 0.3) | 0.002 d |
| Cytomegalovirus infection, n (%) | 29 (5.3) | 17 (4.7) | 12 (6.6) | 0.453 b |
HU = Hounsfield units; HLA = human leukocyte antigen; eGFR = estimated glomerular filtration rate; PTH = parathyroid hormone; a eGFR—CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) (mL/min per 1.73 m20; b p-value by chi-square test; c p-value by Student’s t-test; d p-value by Mann–Whitney U test; e data available for 462 patients.