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. 2021 Jan 15;22(2):808. doi: 10.3390/ijms22020808
AKT1 the serine-threonine protein kinase
ALL acute lymphoblastic leukemia
BCP-ALL B-cell precursor acute lymphoblastic leukemia
BSAP B-cell-specific protein activator factor
CIR cumulative incidence of relapse
CNAs copy number alterations
DFR disease free of recurrence
DIC disseminated intravascular coagulation
DR Downregulation
EGIL The European Group for the Immunologic Classification
ESF event-free survival
ETP-ALL Early T-cell precursor ALL
GSI γ-secretase inhibitors
HD heterodimerization domain
JAK 1 janus kinase 1
LBL acute lymphoblastic lymphoma
LDH lactate dehydrogenase
MRD minimal residual disease
NGS new generation sequencing
OE Overexpression
OS overall survival
PDGFRb platelet dderived growth factor b
PEST (-Pro-Gln-Ser-Thr-) domain.
PIP2 phosphatidylinositol (4,5) P2
PIP3 phosphatidylinositol (3,4,5) P3
PRC polycomb group complex
RFS relapse-free survival
SNV single nucleotide variants
STAT5B signal transducer and activator of transcription 5B
T-ALL T-cell acute lymphoblastic leukemia
TCR T cell antigen receptor
TKI tyrosine kinase inhibitor
WBC white blood cell