Table 1.
General characteristics of experimental animals.
| Parameter | Wistar | HTG |
|---|---|---|
| SBP (mmHg) | 118.48 ± 1.76 | 135.67 ± 2.14 * |
| BW (g) | 425 ± 11 | 388 ± 10 * |
| HW (mg) | 1.23 ± 0.29 | 1.06 ± 0.23 |
| TL (mm) | 39.48 ± 0.51 | 41.71 ± 0.38 |
| HW/BW (mg/g) | 2.93 ± 0.05 | 2.57 ± 0.09 * |
| HW/TL (mg/mm) | 31.42 ± 0.66 | 25.47 ± 0.57 * |
| RFW (mg) | 26.8 ± 0.28 | 45.0 ± 0.31 * |
| RFW/TL (mg/mm) | 68.34 ± 6.98 | 108.16 ± 7.23 ** |
| GLU (mmol/L) | 4.8 ± 0.2 | 4.9 ± 0.2 |
| OGTT AUC (mmol/L/2 h) | 790 ± 58 | 907 ± 26 ** |
| TAG (mmol/L) | 1.57 ± 0.14 | 5.26 ± 0.45 *** |
| Chol (mg/dL) | 1.76 ± 0.09 | 1.58 ± 0.05 |
| HDL-C (mmol/L) | 1.32 ± 0.07 | 0.57 ± 0.05 ** |
| NEFA (mmol/L) | 0.212 ± 0.012 | 0.410 ± 0.034 ** |
| TAG in heart (μmol/g) | 1.98 ± 0.23 | 2.42 ± 0.20 |
| TAG in kidney (μmol/g) | 3.45 ± 0.56 | 4.10 ± 0.44 |
| MCP-1 (pg/mL) | 170.0 ± 14.0 | 277.6 ± 30.8 * |
| TNFα (pg/mL) | 1.67 ± 0.24 | 1.84 ± 0.15 |
| IL-6 (pg/mL) | 13.26 ± 1.78 | 15.49 ± 2.67 |
| Leptin (ng/mL) | 2.71 ± 0.13 | 3.56 ± 0.11 ** |
| hsCRP (μg/mL) | 220.9 ± 7.8 | 230.2 ± 16.7 |
| ALT (U/L) | 19.30 ± 2.67 | 33.12 ± 0.93 *** |
| Crea (μmol/L) | 27.38 ± 0.68 | 31.56 ± 1.36 * |
| Urea (mmol/L) | 5.90 ± 0.12 | 7.73 ± 0.19 *** |
SBP, systolic blood pressure; BW, body weight; HW, heart weight; TL, tibia length; HW/BW, heart weight/body weight ratio; HW/TL, heart weight/tibia length ratio; RFW, retroperitoneal fat weight; RFW/TL, retroperitoneal fat weight/tibia length ratio; Chol, total cholesterol; HDL, high-density lipoprotein cholesterol; TAG, triacylglycerols; GLU, fasting glucose; OGTT AUC, the area under the glycemic curve during the oral glucose tolerance test; ALT, alanine-aminotransferase; Crea, creatinine; MCP-1, monocyte chemoattractant protein-1; TNFα, tumor necrosis factorα; NEFA, nonesterified fatty acids; IL-6, interleukin-6; hsCRP, high-sensitivity C-reactive protein. Values are shown as the mean ± S.E.M. * p < 0.05 vs. Wistar rats; ** p < 0.01 vs. Wistar rats; *** p < 0.001 vs. Wistar rats.