Table 2.
Impact of genetic factors and differentiation grading on disease-free survival (DFS) in stage III patients with disease-free survival (IMA).
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P_value | HR (95% CI) | P_value | |
|
EGFR
(with vs. without) |
0.19 (0.04–0.96) | 0.027 | 2.49 (0.31–20.02) | 0.391 |
|
KRAS
(with vs. without) |
6.95 (0.96–50.45) | 0.027 | 85.15 (2.27–3,200.87) | 0.016 |
| PI3K pathway (with vs. without) |
0.12 (0.01–0.99) | 0.023 | 0.05 (0–0.91) | 0.043 |
| Differentiation grading (Poor vs. moderate) |
3.75 (1.00–14.10) | 0.037 | 17.14 (1.32–221.76) | 0.030 |