Table 5.
CoMiSS®: Cow’s Milk-related Symptom Score.
| Symptom | Score | ||||
|---|---|---|---|---|---|
| Crying (only considered if the child has been crying for 1 week or more, assessed by parents) | 0 | ≤1 h/day | |||
| 1 | 1 to 1.5 h/day | ||||
| 2 | 1.5 to 2 h/day | ||||
| 3 | 2 to 3 h/day | ||||
| 4 | 3 to 4 h/day | ||||
| 5 | 4 to 5 h/day | ||||
| 6 | ≥5 h/day | ||||
| Regurgitation | 0 | 0 to 2 episodes/day | |||
| 1 | ≥3 to ≤5 of small volumes | ||||
| 2 | >5 episodes of >1 coffee spoon | ||||
| 3 | >5 episodes of ± half of the feeds in half of the feeds | ||||
| 4 | Continuous regurgitations of small volumes >30 min after each feed | ||||
| 5 | Regurgitation of half to complete volume of a feed in at least half of the feeds | ||||
| 6 | Regurgitation of the complete feed after each feeding | ||||
| Stools (Bristol scale) | 4 | Type 1 and 2 (hard stools) | |||
| 0 | Type 3 and 4 (normal stools) | ||||
| 2 | Type 5 (soft stools) | ||||
| 4 | Type 6 (liquid stools, if unrelated to infection) | ||||
| 6 | Type 7 (watery stools) | ||||
| Skin | 0 to 6 | Atopic eczema head-neck-trunk arms-hands-legs-feet | |||
| Absent | 0 | 0 | |||
| Mild | 1 | 1 | |||
| Moderate | 2 | 2 | |||
| Severe | 3 | 3 | |||
| Urticaria | 0 or 6 | YES | NO | ||
| 6 | 0 | ||||
| RespiratorySymptoms | 0 | No respiratory symptoms | |||
| 1 | Slight symptoms | ||||
| 2 | Mild symptoms | ||||
| 3 | Severe symptoms | ||||
The most relevant papers dealing with CoMiSS are listed in Table 6. CoMISS: Coe’s Milk Related Symptoms Score.