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. 2021 Jan 18;10(1):180. doi: 10.3390/foods10010180

Figure 2.

Figure 2

The effect of LEPE on menopause-related osteoporosis in body composition and blood. (A) BMD (bone mineral density), (B) hip joint BMD, (C) osteocalcin, and (D) CTX-1 (C-terminal telopeptide of type 1 collagen). Sham, control sham-operated rats; Veh, ovariectomized (OVX) rats treated with vehicle; LEPE100, OVX rats treated with Leonurus japonicus Houtt, Eclipta prostrata L., and Pueraria lobata Ohwi extract (LEPE) 100 mg/kg bw; LEPE200, OVX rats treated with LEPE 200 mg/kg bw; E2, positive control, OVX rats injected with estradiol 3.0 µg/kg bw. Data are shown as mean ± SEM (n = 12). a–c Significant differences were analyzed by one-way ANOVA with Tukey’s multiple comparisons between groups (p < 0.05).