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. 2021 Jan 15;22(2):818. doi: 10.3390/ijms22020818

Figure 4.

Figure 4

Changes of ER stress core genes mRNA levels after five weeks of empagliflozin/vehicle oral administration in the liver of ApoE(-/-) mice. The mRNA levels of elf2α, ATF-4, GRP78, CHOP, IRE1, XbP1, ATF-6 and GRP94 were significantly reduced after five weeks of empagliflozin treatment. Data are shown as the mean ± SEM (*: p < 0.05).