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The mRNA and protein levels of apoptosis related molecules. (A) Empagliflozin treatment for five weeks significantly increased the mRNA Bcl2/Bax ratio. (B) Western blot analysis of cleaved caspase-8 with quantitative analyses showing that empagliflozin reduces the protein levels of cleaved caspase-8. Data are shown as the mean ± SEM (*: p < 0.05; **: p < 0.01; I.C: Internal control).
