Table 5.
Risk factors for 30-day mortality according to univariate and multivariable Cox proportional hazards analysis
| Univariate Cox regression analysis | Multivariable Cox regression analysis | |||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p | |
| Female gender | 1.06 | 0.76–1.46 | 0.78 | |||
| Multilobar infiltrates | 1.25 | 0.85–1.85 | 0.458 | |||
| Pleural effusion | 1.28 | 0.86–1.89 | 0.25 | |||
| PSI > 130 points (Class V) | 3.88 | 2.30–6.55 | 0.0001 | 2.87 | 1.64–5.02 | 0.0001 |
| Any in-hospital CV event | 1.99 | 1.36–2.90 | 0.001 | 1.69 | 1.14–2.51 | 0.009 |
| Newly diagnosed decompensated heart failure | 1.62 | 1.56–2.55 | 0.039 | |||
| New onset AF or flutter | 1.04 | 0.64–1.58 | 0.99 | |||
| CAD | 1.02 | 0.64–1.65 | 0.9 | |||
| COPD | 1.04 | 0.71–1.55 | 0.84 | |||
| Stroke/TIA | 1.71 | 0.74–3.93 | 0.20 | |||
| Arterial Hypertension | 0.77 | 0.54–1.09 | 0.145 | |||
| Cancer | 1.69 | 1.10–2.60 | 0.019 | |||
| Dementia | 2.89 | 1.93–4.31 | 0.0001 | 2.41 | 1.58–3.67 | 0.0001 |
| Comorbidities > 3 | 1.74 | 1.16–2.60 | 0.011 | |||
| Acute Kidney Injury during hospitalisation | 2.31 | 1.53–3.49 | 0.0001 | 1.86 | 1.21–2.87 | 0.005 |
| CKD | 1.84 | 1.16–2.92 | 0.013 | |||
AF Atrial fibrillation, CAD Coronary artery disease, COPD Chronic obstructive pulmonary disease, TIA Transient ischemic attack, CKD Chronic kidney disease