Table 8.
Demographic and patient-related preoperative potential prognostic factors for liver and lung recurrence
|
|
Recurrence, n = 58
|
|||||||
|
Liver
|
Lung
|
|||||||
|
No, n = 33 (55.0%)
|
Yes, n = 25 (41.7%)
|
HR (95%CI)
|
P
value
|
No, n = 42 (70.0%)
|
Yes, n = 16 (26.7%)
|
HR (95%CI)
|
P
value
|
|
| Age, yr, mean ± SD | 67.4 ± 12.3 | 68.0 ± 12.3 | 1.00 (0.97-1.03) | 0.945 | 67.3 ± 12.7 | 68.7 ± 11.0 | 1.00 (0.96-1.04) | 0.837 |
| Gender, n (%) | 0.702 | 0.185 | ||||||
| Male | 16 (55.2) | 13 (44.8) | Reference | 19 (65.5) | 10 (34.5) | Reference | ||
| Female | 17 (58.6) | 12 (41.4) | 0.86 (0.39-1.88) | 23 (79.3) | 6 (20.7) | 0.50 (0.18-1.39) | ||
| Preop Hb, g/dL, mean ± SD | 11.28 | 11.93 | 1.16 (0.88-1.53) | 0.296 | 11.4 ± 2.3 | 12.0 ± 2.5 | 1.14 (0.81-1.61) | 0.446 |
| Preop glycemia, g/dL, mean ± SD | 1.08 ± 0.36 | 1.08 ± 0.31 | 1.72 (0.14-10.00) | 0.884 | 1.06 ± 0.33 | 1.14 ± 0.35 | 1.47 (0.12-18.20) | 0.764 |
| Preop total proteins, g/dL, mean ± SD | 6.7 ± 0.7 | 7.1 ± 0.8 | 1.33 (0.56-3.17) | 0.514 | 6.9 ± 0.9 | 6.9 ± 0.5 | 0.87 (0.19-3.93) | 0.861 |
| Preop CEA, n (%) | 0.868 | 0.891 | ||||||
| < 5 ng/mL | 6 (46.2) | 7 (53.8) | Reference | 10 (76.9) | 3 (23.1) | Reference | ||
| ≥ 5 ng/mL | 4 (57.1) | 3 (42.9) | 0.89 (0.23-3.46) | 5 (71.4) | 2 (28.6) | 1.14 (0.18-7.14) | ||
| Missing | 23 | 15 | 27 | 11 | ||||
| BMI, mean ± SD | 26.3 ± 4.9 | 27.8 ± 4.7 | 1.04 (0.94-1.15) | 0.465 | 27.6 ± 4.8 | 25.7 ± 4.6 | 0.96 (0.83-1.13) | 0.646 |
| ASA, n (%) | ||||||||
| 1 | 3 (60) | 2 (40) | Reference | 4 (80) | 1 (20) | Reference | ||
| 2 | 8 (42.1) | 11 (57.9) | 0.64 (0.15-2.75) | 0.544 | 14 (73.7) | 5 (26.3) | 0.46 (0.06-3.38) | 0.447 |
| 3 | 13 (61.9) | 8 (38.1) | 0.34 (0.07-1.55) | 0.163 | 15 (71.4) | 6 (28.6) | 0.31 (0.04-2.35) | 0.258 |
| 4 | 3 (100) | 0 (0.0) | 0.30 (0.01-7.69) | 0.471 | 2 (66.7) | 1 (33.3) | 2.09 (0.16-27.56) | 0.573 |
| Missing | 6 | 4 | 7 | 3 | ||||
| Presentation with occlusion, n (%) | 0.465 | 0.470 | ||||||
| No | 5 (62.5) | 3 (37.5) | Reference | 6 (75) | 2 (25) | Reference | ||
| Yes | 6 (46.2) | 7 (53.8) | 1.58 (0.46-5.44) | 9 (69.2) | 4 (30.8) | 1.89 (0.34-10.61) | ||
| Missing | 23 | 15 | 27 | 11 | ||||
| Tumour site, n (%) | ||||||||
| Right colon | 11 (68.7) | 5 (31.3) | Reference | 13 (81.3) | 3 (18.7) | Reference | ||
| Left colon | 11 (42.3) | 15 (57.7) | 2.48 (0.89-6.88) | 0.081 | 20 (76.9) | 6 (23.1) | 1.73 (0.42-7.04) | 0.445 |
| Rectum | 11 (68.7) | 5 (31.3) | 0.98 (0.28-3.41) | 0.972 | 9 (56.3) | 7 (43.7) | 2.34 (0.59-9.32) | 0.226 |
HR: Hazard ratio; OR: Odds ratio; CI: Confidential intervals; Preop: Preoperative value; Hb: Haemoglobin; CEA: Carcinoembryonic antigen; BMI: Body mass index; ASA: American Society of Anaesthesiologists Score.