Tab. 1.

Study group characteristics

No	Age (at administration)	Site of administration	Type of filler	Onset of complication	Signs and symptoms	Ultrasound diagnosis
1	38	lips	HA	12 years	small, hard nodules	massive fibrosis
2	39	lips	HA	3 months	hard nodules	depositions
3	70	cheeks	HA	1 month	skin redness, pain and palpable nodules	depositions
4	50	glabella, nasolabial folds	Princess Filler	6 months	multiple lumps	granulomas
5	46	lips, nasolabial folds	HA	8 months	hard nodules, edema	granulomas
6	30	lips	Teosyal Kiss	3 months	multiple, small, hard nodules	granulomas
7	38	cheeks	Teosyal Kiss	7 years	hard nodules with varying size	depositions
8	64	lips	HA	10 years	subtle paleness of the white roll of the lips, upper lip nodule	fibrosis in the upper lip and persistent depositions
9	44	chin	Juvederm Voluma	1.5 years	chin nodule	depositions
10	32	cheeks, nasolabial folds	Neuvia	2 years	multiple nodules palpable under the skin	depositions
11	38	lips	HA	10 years	hard lip thickening	fibrosis
12	34	lips	HA	3 weeks	dry lips and stinging sensation	inflammation, depositions
13	47	cheeks	HA	3 years	overcorrection on the right side since administration	multiple depositions
14	38	cheeks, temporal region	HA	1 week	Edema of the right cheek and temple	large deposition bulging the temporal muscle
15	37	chin	HA	1 week	chin nodule	massive inflammatory reaction in the subcutaneous tissue