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. 2021 Jan 16;21(2):604. doi: 10.3390/s21020604

Table 2.

Applications of the detection of metal ions by PADs and microPADs using luminescent nanomaterials as receptors.

Target Analyte Sample/Matrix Nanostructured Receptor Sensor Design Signal Acquisition Analytical Characteristics Ref.
Se(IV) Hair, sediment, urine CdTe QDs PAD Fluorescence under
UV irradiation
0.1 ppb Se [72]
Hg(II), Pb(II),
Cu(II)
River water CDs PAD
(microarray)
Smartphone 5.8 nM (Hg)
0.12 µM (Pb)
0.076 µM (Cu)
[73]
Hg(II) Wastewater GQDs
(N, S-codoped)
PAD Digital camera
(UV irradiation)
0.14 nM [74]
Ce(III) River water Carbon dots PAD Naked eye
(UV irradiation)
0.7 µM
(fluorimetry)
[75]
Fe(III) -- N-doped GQDs PAD Naked eye
(UV irradiation)
2.37 µM
(fluorimetry)
[76]
Hg(II) Water, urine CdSe/ZnS QDs
(functionalized with
HDTC)
PAD Naked eye
(UV irradiation)
0.2 ppm Hg [77]
Ag(I), AgNPs River water CdTe QDs PAD Naked eye
(UV irradiation,
distance measurement)
0.01 ppm (Ag) [78]
Se(IV) Tap water, seawater
fish, rice, eggs
AuNCs PAD Naked eye
(UV irradiation)
and fluorimetry
4 ppb (Se) [79]
Al(III) ---- C-dots-R6G PAD Digital camera
(UV irradiation)
and fluorimetry
3.89 × 10−5 M (PAD) [80]
Tri-butyl-Sn Seawater GQDs conjugated with
MIN
PAD Fluorimetry 0.23 ppt [81]
Hg(II), Cu(II) Tap and river
water
CS-CDs Sponge
cellulose
Mobile camera
(UV irradiation)
26 nM (Al);
0.11 and 3 µM (Cu),
by fluorimetry and PAD,
resp.
[82]
Cu(II) Tap water,
Lake water
Hybrid CdTe-CDs PAD Digital camera
(UV irradiation)
0.36 nM
(fluorimetry)
[83]
Cu(II) Urine, tap water,
Sorghum extract
BSA-AuNCs PAD Naked eye
(UV irradiation)
5 nM
(fluorimetry)
[84]
Cu(II), Hg(II) Tap water N-doped CDs µPAD Digital camera
(UV irradiation)
0.1 µM (µPAD);
6.2 nM (Hg), 2.3 nM
(Cu) by fluorimetry
[85]
Cu(II), Hg(II) Tap and lake water CQDs PAD Naked eye 5 (Cu), 3 (Hg) (µM) [86]
Zn(II) Water, blood, cells AuNCS PAD Naked eye
and fluorimetry
3 ppb (fluorimetry)
20 ppb (naked eye
under UV irradiation)
[87]
Co(II) --- ZnS QDs PAD Mobile camera 10 ppm [88]
Cu(II) -- ZnO NPs PAD Mobile camera 10 µM [89]
Hg(II) Tap water
Lake water
CDs PAD Naked eye
(UV irradiation)
0.14 µM [90]
Pb(II) --- CDs PAD Fluorimetry and
naked eye
0.055 µM
(fluorimetry)
[91]
Pb(II) Waters CDs PAD Fluorimetry and
smartphone camera
2.89 nM (fluorimetry)
45.9 nM (PAD)
[92]