Table 2.

Responses for the Box-Behnken experimental design.

Run	Extraction Time (min)	MeOH Conc. (%)	Solvent Volume (mL)	Yield (%)	Tyrosinase Inhibitory Activity (%)	Compound 1 (µg/mg)	Compound 2 (µg/mg)	Sum of Compounds 1 and 2 (µg/mg)
1	40	40	87.5	2.60	49.79	−0.28	−4.15	−4.44
2	100	40	87.5	3.47	73.34	0.69	3.59	4.28
3	40	100	87.5	2.64	88.99	18.53	64.52	83.05
4	100	100	87.5	3.28	88.96	14.38	94.03	108.41
5	40	70	35	2.86	80.29	6.70	13.51	20.21
6	100	70	35	4.01	82.68	5.95	25.01	30.96
7	40	70	140	5.16	80.35	6.80	28.00	34.79
8	100	70	140	6.63	84.83	5.65	26.39	32.03
9	70	40	35	3.39	62.83	−0.05	−2.00	−2.05
10	70	100	35	2.51	88.60	43.39	64.17	107.56
11	70	40	140	4.77	71.82	2.72	13.96	16.67
12	70	100	140	3.47	89.88	11.32	78.64	89.96
13	70	70	87.5	5.06	91.08	12.82	97.69	110.51
14	70	70	87.5	4.18	88.40	12.23	82.92	95.15
15	70	70	87.5	4.24	87.63	11.34	78.91	90.24