Table 1.
Specific (differentially expressed) proteins of parental and resistant cells.
| Cells | Accession | Gene Symbol | Description |
|---|---|---|---|
| SK-MEL-28 | P08195 | SLC3A2 | 4F2 cell-surface antigen heavy chain |
| SK-MEL-28 | Q9ULZ3 | PYCARD | Apoptosis-associated speck-like protein containing a CARD |
| SK-MEL-28 | P06865 | HEXA | Beta-hexosaminidase subunit alpha |
| SK-MEL-28 | P07711 | CTSL | Cathepsin L1 |
| SK-MEL-28 | O00299 | CLIC1 | Chloride intracellular channel protein 1 |
| SK-MEL-28 | P63241 | EIF5A | Eukaryotic translation initiation factor 5A-1 |
| SK-MEL-28 | P04439 | HLA-A | HLA class I histocompatibility antigen, A-3 alpha chain |
| SK-MEL-28 | P19013 | KRT4 | Keratin, type II cytoskeletal 4 |
| SK-MEL-28 | Q92859 | NEO1 | Neogenin |
| SK-MEL-28 | Q02818 | NUCB1 | Nucleobindin-1 |
| SK-MEL-28 | P19338 | NCL | Nucleolin |
| SK-MEL-28 | P10451 | SPP1 | Osteopontin |
| SK-MEL-28 | Q86UD1 | OAF | out at first protein homolog |
| SK-MEL-28 | Q6S8J3 | POTEE | POTE ankyrin domain family member E |
| SK-MEL-28 | Q15262 | PTPRK | Receptor-type tyrosine-protein phosphatase kappa |
| SK-MEL-28 | Q13332 | PTPRS | Receptor-type tyrosine-protein phosphatase S |
| SK-MEL-28 | Q12765 | SCRN1 | Secernin-1 |
| SK-MEL-28 | Q8N474 | SFRP1 | Secreted frizzled-related protein 1 |
| SK-MEL-28 | Q92743 | HTRA1 | Serine protease HTRA1 |
| SK-MEL-28 | P00441 | SOD1 | Superoxide dismutase [Cu-Zn] |
| SK-MEL-28 | P78324 | SIRPA | Tyrosine-protein phosphatase non-receptor type substrate 1 |
| SK-MEL-28 | P08670 | VIM | Vimentin |
| SK-MEL-28-VR2 | O14817 | TSPAN4 | Tetraspanin-4 |
| SK-MEL-28-VR2 | O43505 | B3GNT1 | Beta-1,4-glucuronyltransferase 1 |
| SK-MEL-28-VR2 | O60462 | NRP2 | Neuropilin-2 |
| SK-MEL-28-VR2 | O75874 | IDH1 | Isocitrate dehydrogenase |
| SK-MEL-28-VR2 | P00338 | LDHA | L-lactate dehydrogenase A chain |
| SK-MEL-28-VR2 | P01130 | LDLR | Low-density lipoprotein receptor |
| SK-MEL-28-VR2 | P06276 | BCHE | Cholinesterase |
| SK-MEL-28-VR2 | P07237 | P4HB | Protein disulfide-isomerase |
| SK-MEL-28-VR2 | P32004 | L1CAM | Neural cell adhesion molecule L1 |
| SK-MEL-28-VR2 | P35237 | SERPINB6 | Serpin B6 |
| SK-MEL-28-VR2 | P35613 | BSG | Basigin |
| SK-MEL-28-VR2 | P37802 | TAGLN2 | Transgelin-2 |
| SK-MEL-28-VR2 | P40967 | PMEL | Melanocyte protein PMEL |
| SK-MEL-28-VR2 | P42785 | PRCP | Lysosomal Pro-X carboxypeptidase |
| SK-MEL-28-VR2 | P46926 | GNPDA1 | Glucosamine-6-phosphate isomerase 1 |
| SK-MEL-28-VR2 | P48637 | GSS | Glutathione synthetase |
| SK-MEL-28-VR2 | P48745 | NOV | Protein NOV homolog |
| SK-MEL-28-VR2 | P49641 | MAN2A2 | Alpha-mannosidase 2x |
| SK-MEL-28-VR2 | P52209 | PGD | 6-phosphogluconate dehydrogenase, decarboxylating |
| SK-MEL-28-VR2 | P54819 | AK2 | Adenylate kinase 2, mitochondrial |
| SK-MEL-28-VR2 | P16152 | CBR1 | Carbonyl reductase |
| SK-MEL-28-VR2 | P16930 | FAH | Fumarylacetoacetase |
| SK-MEL-28-VR2 | P17174 | GOT1 | Aspartate aminotransferase, cytoplasmic |
| SK-MEL-28-VR2 | P18669 | PGAM1 | Phosphoglycerate mutase 1 |
| SK-MEL-28-VR2 | P19021 | PAM | Peptidyl-glycine alpha-amidating monooxygenase |
| SK-MEL-28-VR2 | P20618 | PSMB1 | Proteasome subunit beta type-1 |
| SK-MEL-28-VR2 | P22392 | NME1 | Nucleoside diphosphate kinase B |
| SK-MEL-28-VR2 | P25787 | PSMA2 | Proteasome subunit alpha type-2 |
| SK-MEL-28-VR2 | P12955 | PEPD | Xaa-Pro dipeptidase |
| SK-MEL-28-VR2 | P07686 | HEXB | Beta-hexosaminidase subunit beta |
| SK-MEL-28-VR2 | P07996 | THBS1 | Thrombospondin-1 |
| SK-MEL-28-VR2 | P99999 | CYCS | Cytochrome c |
| SK-MEL-28-VR2 | Q01469 | FABP5 | Fatty acid-binding protein, epidermal |
| SK-MEL-28-VR2 | Q96KP4 | CNDP2 | Cytosolic non-specific dipeptidase |
| SK-MEL-28-VR2 | Q9H2E6 | SEMA6A | Semaphorin-6A |
| SK-MEL-28-VR2 | Q9NPF2 | CHST11 | Carbohydrate sulfotransferase 11 |
| SK-MEL-28-VR2 | Q9P2B2 | PTGFRN | Prostaglandin F2 receptor negative regulator |
| SK-MEL-28-VR2 | Q9UBQ6 | EXTL2 | Exostosin-like 2 |
| SK-MEL-28-VR2 | Q9UNW1 | MINPP1 | Multiple inositol polyphosphate phosphatase 1 |
| SK-MEL-28-VR2 | Q9Y281 | CFL2 | Cofilin-2 |
| SK-MEL-28-VR2 | Q6IBS0 | TWF2 | Twinfilin-2 |
| SK-MEL-28-VR2 | Q8NBJ7 | SUMF2 | Sulfatase-modifying factor 2 |
| SK-MEL-28-VR2 | Q8NCW5 | APOA1BP | NAD(P)H-hydrate epimerase |
| SK-MEL-28-VR2 | Q8WVQ1 | CANT1 | Soluble calcium-activated nucleotidase 1 |
| SK-MEL-28-VR2 | Q92520 | FAM3C | Protein FAM3C |
| SK-MEL-28-VR2 | Q06830 | PRDX1 | Peroxiredoxin-1 |
| SK-MEL-28-VR2 | Q14019 | COTL1 | Coactosin-like protein |
| SK-MEL-28-VR2 | Q15084 | PDIA6 | Protein disulfide-isomerase A6 |