Table 4.
Multivariate analysis of mortality. The effect of each factor is expressed as an adjusted odds ratio (CI 95%).
| Adjusted OR | p | |
|---|---|---|
| Demographics | ||
| Age (years) | 1.050 (1.036 to 1.065) | 0.000 |
| Gender (female) | 0.644 (0.471 to 0.881) | 0.006 |
| Hypertension | 1.320 (0.996 to 1.816) | 0.087 |
| Moderate-to-severe dependency | 2.250 (1.515 to 3.342) | 0.000 |
| Clinical manifestations at admission | ||
| Cough | 0.670 (0.483 to 0.929) | 0.016 |
| Confusion | 1.718 (1.149 to 2.569) | 0.008 |
| Tachypnoea | 1.894 (1.397 to 2.566) | 0.000 |
| Wheezing | 1.597 (0.966 to 2.639) | 0.068 |
| Desaturation | ||
| Saturation 90–94% | 1.701 (1.196 to 2.420) | 0.003 |
| Saturation <90% | 4.594 (3.084 to 6.843) | 0.000 |
| Treatment during hospitalisation | ||
| Hydroxychloroquine | 0.662 (0.432 to 1.013) | 0.057 |
| Azithromycin | 0.647 (0.475 to 0.881) | 0.006 |
| Laboratory findings at admission | ||
| Creatinine >1.4 at admission | 1.564 (1.103 to 2.219) | 0.012 |
| LDH >360 at admission | 2.450 (1.757 to 3.416) | 0.000 |
| AST >60 at admission | 2.462 (1.637 to 3.704) | 0.000 |
| ALT >60 at admission | 0.444 (0.274 to 0.720) | 0.001 |
| Glycaemia >125 at admission | 1.405 (1.045 to 1.889) | 0.024 |
| Lymphopenia <800 × 106/L at admission | 1.452 (1.086 to 1.942) | 0.012 |
| Laboratory findings on the seventh day of hospitalisation | ||
| Eosinophil counts increased >80 × 106/L | 0.234 (0.154 to 0.354) | 0.000 |
| LDH increased >1.5× | 10.614 (7.101 to 15.867) | 0.000 |
| Creatinine increased >1.5× | 6.032 (3.528 to 10.315) | 0.000 |
| D-dimer increased >500 | 2.341 (1.718 to 3.189) | 0.000 |
| ALT increased >3× | 0.536 (0.321 to 0.894) | 0.017 |