FIGURE 4.

Additive effect of L-NIL and anisomycin on MMP-9 activity at both pericyte soma and non-soma locations. (A–D) Representative examples of pericyte-associated FITC-gelatin activation in the vehicle group (A), and with administration of high-dose L-NIL (B), anisomycin (C), and L-NIL + anisomycin (D). (E,F) Effect of inhibitors on proportion of leakage sites with FITC-gelatin activity at pericyte soma or non-soma locations. Each bar shows FITC-gelatin positive leakage sites over total number of leakage sites observed.