ACE-011	Sotatercept
ACE-536	Luspatercept
ActRIIA	Activin receptor type IIA
ActRIIA-Fc	Fc domain of human IgG1
ActRIIB	Activin receptor type IIB
ActRIIB-Fc	Fc domain of human IgG1
ALK1-7	Activin-like receptors
Bcl-x	B-cell lymphoma-extra large
BFU-E	Erythroid burst-forming units
BMPs	Bone morphogenetic proteins
CD34+	Cluster of differentiation 34+
CFU-E	Erythroid colony-forming units
CKD	Chronic kidney disease
DAG	Dyacylglicerol
DCYTB	Duodenal Cytochrome B
DMT1	Divalent Metal Transporter 1
DOAJ	Directory of open access journals
EPC	EPO-producing cells
EPO	Erythropoietin
EPO-R	Erythropoietin receptor
ESAs	Erythropoiesis-stimulating agents
FASL	FAS ligand
GDF11	Growth/differentiating factor 11
HI-E	Hematological erythroid improvement
HIF	Hypoxia inducible factor
HIF-PHD enzymes	Hypoxia inducible factor prolyl hydrolase domain enzymes
HSC	Hematopoietic stem cells
HSP70	Heat shock protein 70
IL-3	Interleukin 3
IP3	Inositol-1,4,5-trisphospate
I-SMAD	Inhibitory small mother against decapentaplegic
JAK 2	Janus Kinase 2
LD	Linear dichroism
MAD	Mothers against decapentaplegic
MDS	Myelodysplastic syndromes
MDS-RS	Myelodysplastic syndromes with ring sideroblasts
NTDT	Non-transfusion-dependent thalassemia
PI	Phosphoinositides
PIP2	Phosphatidylinositol (4,5) bisphosphate
PIP3	PtdIns(3,4,5)P3
PI3K	Phosphatidilinositol 3-kinases
PLCs	Phospholipases C
p-SMAD	Phosphorylated small mother against decapentaplegic
ROS	Radical oxygen species
R-SMAD	Regulatory small mother against decapentaplegic
SCF	Stem cell factor
SF3B1	Splicing factor 3B subunit 1
SMAD	Small mother against decapentaplegic
STAT5	Signal Transducer and Activator of Transcription 5
TDT	Transfusion-dependent thalassemia
TEA	Treatment-emergent adverse events
TGF	Transforming growth factor
TNF	Tumor necrosis factor
WHO	World Health Organization