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. 2021 Jan 8;13(1):77. doi: 10.3390/pharmaceutics13010077

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Relative expression levels of the genes GBP1 (a,b), GBP5 (c,d), GNLY (e,f), BATF2 (g,h), IGHA1 (i,j), IGHG2 (k,l), FCGR1A (m,n), and FCGR1B (o,p) in responders (R, green) and non-responders (NR, orange) at time 0 (t = 0) and at two weeks (t = 2) after initiation of anti-TNF therapy. Expression values were normalized to the ACTB and RPL4 genes. Values are expressed as mean (horizontal line) and standard error of the mean (SEM); n, sample size; * p value < 0.05 vs. control (unpaired t test).

Relative expression levels of the genes GBP1 (a,b), GBP5 (c,d), GNLY (e,f), BATF2 (g,h), IGHA1 (i,j), IGHG2 (k,l), FCGR1A (m,n), and FCGR1B (o,p) in responders (R, green) and non-responders (NR, orange) at time 0 (t = 0) and at two weeks (t = 2) after initiation of anti-TNF therapy. Expression values were normalized to the ACTB and RPL4 genes. Values are expressed as mean (horizontal line) and standard error of the mean (SEM); n, sample size; * p value < 0.05 vs. control (unpaired t test).