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. 2021 Jan 15;9(1):80. doi: 10.3390/biomedicines9010080

Figure 5.

Figure 5

(A) Schematic illustration for the preparation of MnO2-PEG-cRGD/Ce6 for synergistic photothermal/photodynamic (PTT/PDT) therapy. (B) Relative viabilities of PC3 cells after incubation with free Ce6, MnO2-PEG-cRGD with 660 nm light irradiation, or MnO2-PEG-cRGD/Ce6 with or without 660 nm light irradiation (0.6 W cm−2, 10 min, *** p < 0.001, ** p < 0.01). (C) Fluorescence images of calcein acetoxymethyl ester (Calcein-AM, green)/propidium iodide (PI, red) double stained cells after different treatments. The images are reproduced with permission from [103].