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. 2021 Jan 15;9(1):80. doi: 10.3390/biomedicines9010080

Table 3.

Recent photothermal (PT)-Photoacoustic Imaging(PAI) multimodal studies classified by their characteristics.

PT-Multimodality Key Material Formulation Modification/Functionalization/Hybridization Experimental Ref.
x Black phosphorus (BP) Quantum dot Sulfonic ester of the titanium ligand (TiL4) MCF-7, 293T cells, and MCF-7 tumor-bearing Balb/c nude mice [103]
Layered double hydroxide (LDH) Nanosheet CoMn and chlorin e6 (Ce6) HeLa, U87mg, HepG2, 4T1 cells, and HeLa tumor-bearing Balb/c nude mice [106]
Reduced graphene oxide (rGO) Nanocomposite Polyethylene glycol (PEG), indocyanine green (ICG) Hela cells, Balb/c nude mice [107]
o Antimonene (AM) Liquid phase nanoflake PEG 293T, MCF-7, SK-BR3, T47D cells, and MCF-7 tumor-bearing mice [108]
Antimony (III) Selenide (Sb2Se3) Nanosheet Poly(vinyl pyrrolidone) (PVP) 4T1, MBA-MD-231 cells, Balb/c nude mice [109]
Tantalum carbide
(Ti3C2 MXene)
Nanosheet SP (soybean phospholipid) and doxorubicin (DOX) 4T1 cells, 4T1-inoculated mice [94]
Tantalum carbide (Ta4C3 Mxene) Nanosheet MnO, SP 4T1 cells, Kunming mouse, 4T1 tumor-bearing mice, and Balb/c nude mice [110]
MXene (Ta4C3) Nanosheet Manganese oxide nanoparticles (MnOx) and SP 4T1 cells and 4T1 tumor-bearing nude mice [111]
Bismuth selenide
(Bi2Se3)
Nanosheet None MCF-7 cells and MCF-7 tumor-bearing Balb/c nude mice [112]
Bi2O2Se Quantum dot None A549, MCF-7 cells, and MCF-7 tumor-bearing Balb/c nude mice [113]
Bi2Se3 Nanodish HA, polypyrrole (PPy), and zinc phthalocyanine (ZnPc) 4T1 cells and 4T1 tumor-bearing Balb/c nude mice [114]
Molybdenum disulfide (MoS2) Nanoconjugate Hyaluronic acid (HA) HCT116 cells and HCT116-inoculated mice [115]
MoS2 Nanosheet Iron oxide nanoparticle (IONP) and PEG Balb/c mice and 4T1 tumor-bearing mice [116]
MoS2 and Bi2S3 Nanosheet PEG L929 cells and 4T1 tumor-bearing Balb/c nude mice [117]
Palladium (Pd) Nanosheet DOX, Zeolitic imidazolate frameworks (ZIF-8), Polydopamine (PDA) WBCs (white blood cells) from mice, 4T1 cells, and 4T1 tumor-bearing mice [118]
Pd Nanoplate Au and PEG 4T1 tumor-bearing Balb/c mice [119]
Titanium (Ti) Nanosheet PEG SMMC-7721, B16, J774A.1 cells, and Balb/c nude mice [120]
Germanene Quantum dot PEG MCF-7, 4T1, H1299, HeLa cells, and Balb/c mice [121]
Boron Nanosheet PEG HeLa, PC3, MCF-7, A549 cells, and MCF-7 tumor-bearing mice [104]
Manganese boride Nanosheet Bi 4T1 cells and 4T1 tumor-bearing mice [122]
MnO2 Nanosheet None U87MG cells and U87MG tumor-bearing mice [123]
Tungsten disulfide (WS2) Nanosheet PVP L929, HT29 cells, KM mice, and HT29 tumor-bearing KM mice [124]
Co9Se8 Nanoplate Poly(acrylic acid) (PAA), DOX HepG2 cells, HepG2 tumor-bearing Balb/c-nude mice [125]
Au Nanoring None Raw 264.7 cells, U87MG tumor-bearing nude mice [126]
Cu2MnS2 Nanoplate Monomethoxycarboxyl polyethylene glycol (mPEG-COOH) HeLa, S180 cells, and S180 tumor-bearing Balb/c nude mice [127]