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. 2021 Jan 16;13(1):248. doi: 10.3390/nu13010248

Table 4.

Objective sleep outcomes for the placebo, DHA-rich, and EPA-rich treatment groups. Post-dose estimated marginal means and standard error (SE) are presented with F and p values of the main effects from the linear mixed models.

Variable Treatment Post-Dose Main Effects
n Mean SE F p
Latency (minutes) Placebo 74 4.31 a 0.21 Treatment 3.68 0.026
DHA-rich 3.76 a 0.26
EPA-rich 3.98 0.27 Treatment × Night 2.28 0.009
Efficiency (%) Placebo 72 90.30 a,T 0.50 Treatment 3.68 0.030
DHA-rich 92.02 a 0.49
EPA-rich 91.85 T 0.57 Treatment × Night 1.47 0.138
Total Minutes in bed (minutes) Placebo 74 484.51 8.13 Treatment 3.29 0.039
DHA-rich 494.85 b 6.63
EPA-rich 467.10 b 8.55 Treatment × Night 0.851 0.598
Total Sleep Time (Minutes) Placebo 73 437.91 7.56 Treatment 4.06 0.018
DHA-rich 455.17 b 6.18
EPA-rich 427.28 b 8.08 Treatment × Night 1.20 0.281
Wake after Sleep Onset (minutes) Placebo 72 42.02 2.42 Treatment 2.55 0.084
DHA-rich 35.84 2.14
EPA-rich 34.77 2.74 Treatment × Night 1.29 0.225
Number of Awakenings Placebo 74 17.50 0.99 Treatment 0.813 0.446
DHA-rich 15.87 0.88
EPA-rich 16.20 1.08 Treatment × Night 1.19 0.289
Average Awakening Length (minutes) Placebo 74 2.44 0.11 Treatment 0.576 0.564
DHA-rich 2.29 0.09
EPA-rich 2.38 0.12 Treatment × Night 1.50 0.126
Sleep Fragmentation Index Placebo 74 22.89 1.28 Treatment 0.802 0.451
DHA-rich 20.80 1.11
EPA-rich 22.22 1.38 Treatment × Night 1.90 0.036

a = significant difference between active and placebo groups, p < 0.050; b = significant difference between the active treatment groups, p < 0.050; T = trend towards a significant difference between active and placebo groups, p < 0.100.