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MALDI-TOF MS data showing the KAT8 (2 μM)-catalysed acetylation of H4K*16 histone peptides (100 μM) in the presence of AcCoA co-substrate (300 μM) (a–p); Overlaid MS spectra of KAT8-catalysed reactions (red) and no enzyme control reactions (black) that were quenched after being incubated for 3 h at 37 °C.
