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. 2021 Jan 16;22(2):872. doi: 10.3390/ijms22020872
ADP Adenosine diphosphate
AIM2 Absent in melanoma 2
ALRs (AIM2)-like receptors
Apaf-1 Apoptotic protease activating factor
ASC Apoptosis-associated speck-like protein containing a caspase-activation and recruitment domain (CARD)
Bcl B-cell lymphoma
BIR Baculovirus IAP (inhibitor of apoptosis protein) repeat
BMDCs Bone marrow derived dendritic cells
BRCA1 Breast cancer type-1
BRCC3 BRCA1/BRCA2- containing complex, subunit 3
c-FLIP FLICE-like inhibitory protein
CAPS Cryopyrin-associated periodic syndrome
CARD Caspase-activation and recruitment domain
CDL CARD domain linker
CIAS1 cold induced autoinflammatory syndrome 1
CLR C-type lectin receptor
COPs CARD-only proteins
COS-1 CV-1 in Origin with SV40 genes
COVID-19 Coronavirus disease 2019
DAMPs Danger-associated molecular patterns
DD Death domain
DEDs Death-effector domain
DEFCAP Death Effector Filament-forming Ced-4-likeApoptosis Protein
DUBs Deubiquitinating enzyme
EM Electron microscopy
FADD Fas-associated protein with death domain
FBXL2 F-box L
FBXO3 F-box O3
FLICE Caspase-8/FADD-like IL-1β-converting enzyme
FP Fluorescence polarization
FRET Fluorescence resonance energy transfer
GFP Green-fluorescent protein
GLMN Glomulin
GSDMD Gasdermin D
HD helical domain
HDAC Histone deacetylases
HIN Hematopoietic, Interferon-inducible, Nuclear localization
IAPs Inhibitor of apoptosis proteins
IC50 Inhibitory concentration
ICE Interleukin 1β-converting enzyme
ICE Interleukin-1beta converting enzyme
IFI16 Gamma-interferon-inducible protein
IFN Interferon
IKK-γ Inhibitor of nuclear factor kappa-B kinase subunit gamma
IL Interleukin
INCA Inhibitors of NFAT-calcineurin association
IPAF Ice protease activating factor
IRF4 Interferon regulatory factor
ITC Isothermal titration calorimetry
JNK Jun N-terminal kinase
LPS Lipopolysaccharide
LRRs Leucine- rich repeat
LTA Lipoteichoic acid
LUBAC linear ubiquitin chain assembly complex
MALS Multiangle light scattering
MALT1 Mucosa-associated lymphoid tissue lymphoma translocation protein 1
MAPK Mitogen-activated protein kinase
MAPL Mitochondria-associated protein ligase
MARCH7 Membrane associated ring finger (C3HC4) 7
MAVS Mitochondrial antiviral-signaling protein
MBP Maltose-binding protein
MLKL Mixed lineage kinase domain like pseudokinase
MNDA Myeloid cell nuclear differentiation antigen
MSU Monosodium urate
Mul1 Mitochondrial E3 Ubiquitin Protein Ligase 1
NAIP NLR family of apoptosis inhibitory protein
NALP NACHT, LRR and PYD domains-containing proteins
NBD Nucleotide binding domain
NEK7 NIMA-related kinase 7
NEMO NF-kappa-B essential modulator
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
NLRC NLR family CARD domain-containing protein
NLRP Nod-like receptor protein
NLRP3 NLR family pyrin domain containing 3
NLRs NOD-like receptors
NMR Nuclear magnetic resonance
NOD Nucleotide-binding oligomerization domain
OB Oligonucleotide/oligosaccharide binding)
PAMPs Pathogen-associated molecular patterns
PAO Phenylarsine oxide
PKA protein kinase A
PKD protein kinase D
POPs PYD-only proteins
PP2A protein phosphatase 2 A
PRRs Pathogen recognition receptors
PTM Post-translation modifications
PTPase Protein tyrosine phosphatase
PTPN22 Protein tyrosine phosphatase nonreceptor type 22
PYCARD PYD and CARD domain-containing
PYD Pyrin domain
PYHIN Pyrin + HIN
PYPAF1 PYRIN-containing APAF1-like protein 1
RAIDD RIP-associated ICH1/CED3-homologous protein with a death domain
RICK RIP-like interacting CLARP kinase
RIP2 Receptor-interacting protein 2
RMSD Root-mean-square deviation
RNO Regulated by nitric oxide
ROS Reactive oxygen species
SARS-Cov-2 Severe acute respiratory syndrome coronavirus 2
SCF Skp-Cullin-F box
SEC Size-exclusion chromatography
SHARPIN Shank-associated RH domain-interacting protein
STAT1 Signal transducer and activator of transcription
TEV Tobacco etch virus.
TH2 T-helper cell type 2
TLR Toll-like receptors
TMS Target of Methylation-induced Silencing-1
TNF Tumor necrosis factor
TPA 12-O-tetradecanoylphorbol-13-acetate
TRAF3 TNF receptor associated factor 3
TRIF TIR-domain-containing adapter-inducing interferon-β
TRIM Tripartite motif
WHD winged helical domain
WHO World health organization