Table 4.
Cognitive effects of D3R preferring partial agonists.
| Compound | Behavioral Assay | Impairing Agent | Species | Effect | References |
|---|---|---|---|---|---|
| BP-897 | water labyrinth | FG-7142; scopolamine | rat | + | [194] |
| cariprazine | water labyrinth | scopolamine | rat | + | [150] |
| T-maze | PCP | mouse | + | [209] | |
| attentional set-shifting | PCP | mouse | + | [209] | |
| social recognition memory | PCP | mouse | + | [209] | |
| novel object recognition | delay | rat | + | [210] | |
| novel object recognition | neonatal PCP, social isolation | rat | + | [210] | |
| novel object recognition | PCP | rat | + | [205] | |
| operant reversal learning | PCP | rat | + | [205] | |
| 5-choice serial reaction time test | PCP | rat | + | [206] |
+; improving effect.