Table 3.
Perinatal and neonatal data of the study population (n = 604).
| Variable | Asymptomatic SARS-CoV-2 Positive Patients n = 174 |
SARS-CoV-2 Negative Patients n = 430 |
p-Value |
|---|---|---|---|
| Perinatal data | |||
| Gestational age at delivery (weeks) | 39.0 (31–42) | 39.1 (28–42) | NS |
| Preterm delivery (below 37 weeks) | 7.5 (13) | 6.5 (28) | NS |
| Stillbirth | 1.1 (2) | 0.0 (0) | NS |
| PROM | 17.8 (31) | 10.2 (44) | 0.011 |
| PROM in nulliparous women | 26.2 (17/65) | 11.9 (21/177) | 0.007 |
| PPROM | 2.9 (5) | 1.2 (5) | NS |
| Onset of labor | |||
| Programmed caesarean section | 6.9 (12) | 4.4 (19) | NS |
| Spontaneous | 54.0 (94) | 61.4 (264) | |
| Induced | 39.1 (68) | 34.2 (147) | |
| Type of delivery | |||
| Caesarean | 20.7 (36) | 17.2 (74) | NS |
| Vaginal | 70.1 (122) | 67.2 (289) | |
| Vacuum or forceps | 9.2 (16) | 15.6 (67) | |
| Gestational hypertension | 6.4 (11) | 5.8 (24) | NS |
| Preeclampsia | |||
| Mild/moderate | 2.3 (4) | 4.9 (21) | NS |
| Severe | 1.7 (3) | 0.5 (2) | |
| Obstetric hemorrhage | 3.4 (6) | 4.7 (20) | NS |
| Thrombotic risk | |||
| Low | 82.2 (143) | 76.3 (328) | NS |
| Medium | 16.1 (28) | 19.8 (85) | |
| High | 1.7 (3) | 3.0 (13) | |
| Neonatal data | |||
| Male sex | 50.6 (86/170) | 48.2 (205/425) | NS |
| Birth weight (grams) | 3187 (315–4640) | 3249 (900–4610) | NS |
| 1’ Apgar score | 9 (0–10) | 9 (1–10) | NS |
| 5’ Apgar score | 10 (0–10) | 10 (5–10)1 | NS |
| Umbilical artery pH | 7.26 (7.04–7.42) | 7.26(6.90–7.46) | NS |
| NICU admission | 6.9 (12) | 1.6 (7) | 0.001 |
| Days in NICU | 13.2 (1–48) | 11.2 (5–17) | NS |
| Cause of NICU admission: | NS | ||
| Prematurity | 25 (3/12) | 71.4 (5/7) | NS |
| Respiratory distress | 16.7 (2/12) | 14.3 (1/7) | NS |
| COVID-19 protocol | 33.3 (4/12) | 0.0 (0/7) | NS |
Data are shown as mean/range, or percentage(n). p-values obtained by Mann–Whitney’s U test for continuous variables and Pearson chi-squared or Fisher’s exact test for categorical variables. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; NS, nonsignificant; PROM, Premature rupture of membranes; PPROM, Preterm premature rupture of membranes; NICU, neonatal intensive care unit.