AF4 |
Asymmetrical Flow-field-flow-fractionation |
ANOVA |
Analysis of variance |
AUC |
Analytical Ultracentrifuge |
CHOL |
Cholesterol |
DC-CHOL |
3b-(N-(N′,N′-dimethylaminoethane)-carbamoyl) cholesterol hydrochloride |
DLS |
Dynamic Light scattering |
DOPE |
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine |
DOTAP |
1,2-dioleoyl-3-timethylamonium-propane |
DPPC |
1,2-dipalmitoyl-sn-glycero-3-phosphocholine |
DSPC |
1,2-distearoyl-sn-glycero-3-phosphocholine |
ELISA |
Enzyme-linked immunosorbent assay |
ELS |
Electrophoretic Light Scattering |
EMA |
European Medicinal Agency |
EUNCL |
European Nanomedicine Characterization Laboratories |
FDA |
Food and Drug Administration |
Hep G2 |
Human Hepatocarcinoma G2 cell line |
HSPC |
Hydrogenated phosphatidylcholine |
ICH-S8 |
Guideline S8 (Immunotoxicology studies for human pharmaceuticals) of the EMA International Council on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) |
ISO |
International Standards Organization |
JRC |
Joint Research Centre |
LAL |
Limulus Amoebocyte Lysate |
LDH |
Lactate dehydrogenase |
MTT |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H tetrazolium bromide |
NM |
Nanomaterial |
PBMC |
Peripheral blood mononuclear cells |
PBS |
Phosphate Buffer Saline |
PC |
Phosphatidylcholine |
PDI |
Polydispersity Index |
PSD |
Particle Size Distribution |
SD |
Standard Deviation |
TLR4 |
Toll-like-receptor 4 |
USNCL |
National Cancer Institute-Nanotechnology Characterization Laboratory |