Table 1.
Patient, imaging and biopsy characteristics by PCa diagnosis at repeat FB
| PCa on Rebiopsy |
|||
|---|---|---|---|
| No | Yes | p Value | |
| No. lesions/total No. (%) | 110/131 (84) | 21/131 (16) | – |
| Median age (range) | 60.0 (45.0–78.0) | 62.0 (47.0–74.0) | 0.451 |
| Median ng/ml prebiopsy PSA (range) | 5.12 (1.23–24.80) | 4.97 (1.67–13.22) | 0.205 |
| Median cm initial lesion diameter (range) | 0.80 (0.30–3.0) | 0.90 (0.30–2.1) | 0.232 |
| No. max initial GS/total No. (%): | 0.121 | ||
| Benign | 55/110 (50) | 7/21 (33.3) | |
| 3 + 3 | 42/110 (38.2) | 13/21 (61.9) | |
| 3 + 4 | 13/110 (11.8) | 1/21 (4.8) | |
| No. anterior lesions/total No. (%) | 31/131 (28.2) | 4/21 (19.0) | 0.282 |
| No. initial MRI suspicion score/total No. (%): | 0.821 | ||
| Low | 35/110 (31.8) | 7/21 (33.3) | |
| Moderate | 73/110 (66.4) | 14/21 (66.7) | |
| High | 2/110 (1.8) | 0/21 (0) | |
| Median ng/ml repeat biopsy PSA (range) | 5.31 (0.83–36.62) | 4.82 (1.28–21.35) | 0.422 |
| Median days to repeat (range): | |||
| mpMRI | 497.5 (240–1,694) | 475.0 (364–2,742) | 0.537 |
| Biopsy | 530.0 (108–2,581) | 517.0 (364–2,418) | 0.900 |
| Median cm final lesion size (range) | 0.750 (0.30–3.10) | 1.10 (0.30–2.30) | 0.060 |
| Mean ± SD lesion size increase (mm) | −0.316 ± 1.993 | 0.710 ± 2.444 | 0.104 |
| Mean ± SD growth rate (mm/yr) | −0.203 ± 1.082 | 0.143 ± 1.573 | 0.143 |
| Mean ± SD PSA increase (ng/ml) | 0.25 ± 3.53 | 0.45 ± 2.58 | 0.115 |