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. Author manuscript; available in PMC: 2021 Jan 25.
Published in final edited form as: Mol Cancer Ther. 2017 Mar 6;16(6):1021–1030. doi: 10.1158/1535-7163.MCT-16-0511

Figure 4.

Figure 4.

Ibrutinib enhanced the effect of paclitaxel on the growth of an ABCC10-overexpressing HEK293/ABCC10 cell xenograft model in athymic nude mice. A, Images of excised HEK293/ABCC10 tumors tissues from different mice are shown on the 18th day after treatment (n = 7). B, Changes in tumor volume with time in ABCC10-overexpressing xenograft model are shown. C, Mean weight (n= 7) of the excised HEK293/ABCC10 tumors from the mice treated with vehicle, ibrutinib, paclitaxel, or the combination of ibrutinib and paclitaxel. Error bars, SD. *, P < 0.05 versus vehicle group; #, P < 0.05 versus the paclitaxel group. D, The average body weight before and after treatments.