Table 2.
Baseline characteristics and outcome of patients with moderate to severe acute respiratory distress syndrome in this study
| Characteristics | Non-CRRT (n = 33) | CRRT (n = 37) | P value |
|---|---|---|---|
| Age, month | 24 (9–53) | 35 (12–52) | 0.667 |
| Male, n (%) | 19 (57.58) | 22 (59.46) | 0.873 |
| PRISM III | 15 (12–18) | 17 (15–20) | 0.016 |
| BMI, kg/m (2) | 14.70 (12.65–16.86) | 14.00 (12.70–16.38) | 0.778 |
| Co-morbidity, n (%) | |||
| Immune system disease | 1 (3.03) | 4 (10.81) | 0.207 |
| Genetic metabolic disease | 1 (3.03) | 0 (0) | 0.286 |
| Leukemia/tumor | 6 (18.18) | 7 (18.92) | 0.937 |
| Complication, n (%) | |||
| Hepatic failure | 2 (6.06) | 1 (2.70) | 0.489 |
| AKI | 9 (27.27) | 25 (67.57) | 0.001 |
| Brain dysfunction | 1 (3.03) | 1 (2.70) | 0.935 |
| Gastrointestinal dysfunction | 2 (6.06) | 3 (8.11) | 0.740 |
| Pancreatitis | 0 (0) | 2 (5.41) | 0.175 |
| OI | 7.69 (6.46–9.50) | 13.15 (10.00–14.78) | < 0.001 |
| PaCO2, mmHg | 55.00 (38.00–61.00) | 45.00 (34.50–62.00) | 0.225 |
| Mechanical ventilation settings | |||
| PIP, cmH2O | 26 (25–28) | 29 (27–31) | < 0.001 |
| PEEP, cmH2O | 9 (8–10) | 12 (11–14) | < 0.001 |
| FiO2 | 0.55 (0.50–0.74) | 0.70 (0.60–0.88) | 0.002 |
| Duration of mechanical ventilation, day | 6 (4–9) | 8 (6–15) | 0.012 |
| Length of PICU stay, day | 10 (6–17) | 14 (10–20) | 0.047 |
| Length of hospital stay, day | 19 (12–30) | 24 (17–35) | 0.081 |
| Hospital mortality, n (%) | 11 (33.33) | 16 (43.24) | 0.395 |