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. 2021 Jan 15;10(1):169. doi: 10.3390/cells10010169

Figure 5.

Figure 5

CD4+ T cells express CD226. (A–F) Analysis of CD112 binding partner expression on T cells. CD226 (A) and T cell immunoreceptor Ig tyrosine (TIGIT) (B) expressions on freshly isolated splenic CD4+ T cells (red) and in vitro generated TH1 cells (blue). (C) Characterisation of naïve, effector/memory and central memory T cells based on CD44 and CD62L expressions of splenic CD4+ T cells. (D) CD226 (left) and TIGIT (right) expression on naïve (red), effector/memory (green) and central memory (black) T cells. Representative graphs from one out of three similar experiments are shown. (E,F) Percentages of CD226+ (E) or TIGIT+ (F) T cells. Teff/mem: effector/memory; Table 3. 5. CD112 Deficiency Reduces Homing of T Cells to the Spleen.