Table 3.
The top 20 DEGs identified by differential expression profiling from RNA extracted by amygdala pyramidal neurons Comparison between OPTO FEAR vs. OPTO NOT FEAR groups.
| Gene Symbol | Gene Name | Fold Change (log2 Scale) |
OPTO FEAR adj.mean |
OPTO NOT FEAR adj.mean |
|---|---|---|---|---|
| Ube2ql1 | ubiquitin-conjugating enzyme E2Q family-like 1 | −5.13 | 5.54 | 194.27 |
| Slc6a17 | solute carrier family 6 (neurotransmitter transporter), member 17 | −5.12 | 12.86 | 448.21 |
| Papss2 | 3′-phosphoadenosine 5′-phosphosulfate synthase 2 | −4.57 | 9.79 | 232.51 |
| Hap1 | huntingtin-associated protein 1 | −4.29 | 13.22 | 258.18 |
| Ngef | neuronal guanine nucleotide exchange factor | −4.28 | 18.41 | 358.22 |
| Cpm | carboxypeptidase M | 4.24 | 871.36 | 45.96 |
| Thy1 | thymus cell antigen 1, theta | −4.22 | 88.57 | 1649.90 |
| Slc6a9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 4.16 | 1202.20 | 67.13 |
| Arpp21 | cyclic AMP-regulated phosphoprotein, 21 | −4.15 | 33.80 | 599.42 |
| Enc1 | ectodermal-neural cortex 1 | −4.10 | 54.26 | 928.57 |
| Celf5 | CUGBP, Elav-like family member 5 | −4.08 | 12.58 | 212.32 |
| Ermp1 | endoplasmic reticulum metallopeptidase 1 | 4.04 | 1016.54 | 61.64 |
| Ptprg | protein tyrosine phosphatase, receptor type, G | −4.04 | 36.77 | 603.55 |
| Cxcl14 | chemokine (C-X-C motif) ligand 14 | −4.02 | 19.49 | 315.59 |
| Chrna4 | cholinergic receptor, nicotinic, alpha polypeptide 4 | −4.01 | 3.93 | 63.10 |
| Arsg | arylsulfatase G | 4.01 | 580.93 | 36.15 |
| Kcnq2 | potassium voltage-gated channel, subfamily Q, member 2 | −4.00 | 27.21 | 436.00 |
| Sfxn1 | sideroflexin 1 | −3.99 | 15.50 | 246.04 |
| Thrb | thyroid hormone receptor beta | −3.91 | 13.85 | 208.27 |
| Lmo3 | LIM domain only 3 | −3.89 | 12.43 | 183.70 |