Figure A1.

Graphical Representation of Association Rules with Septic Shock (ICD9 = 785.52) as a consequent. Diagnosis codes for the patients in the cohort were obtained and Association Rule Mining [35] was run to mine for relationships between comorbidities. In the study, “items” are diagnosis codes. Items are connected to rules using directional edges. For nodes representing rules, edges pointing from codes to rule vertices indicate antecedent items and an edge from a rule to an item indicates the consequent item. The reader is referred to [58] for more details about the visualization. 511.9: Unspecified pleural effusion; 401.9: Unspecified essential hypertension; 995.2: Severe sepsis; 038.9: Unspecified septicemia; 518.81: Acute respiratory failure; EP751: Other congenital anomalies of digestive system: 584.9: Acute kidney failure.