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miR-424-5p regulates cytokine secretion in coculture model of MM231/peripheral blood mononuclear cells (PBMCs). MM231 cells were transfected with miR-424-5p mimics (A–D) or incubated with EVs-424 or EVs (E–H), and then cocultured with stimulated PBMCs for 16 h. The coculture medium was analyzed for IFN-γ (A,E), TNF-α (B,F), IL-6 (C,G) and IL-10 (D,H) by ELISA. * p < 0.05.
