Table 2.

Serum valganciclovir/ganciclovir trough and peak levels in the different subpopulations.

Patients, n (Prophylaxis/Treatment)	Ganciclovir Serum Levels
	Prophylaxis		Treatment		p Trough	p Peak
	Trough, median (mg/L, IQR)	Peak, median (mg/L, IQR)	Trough, median (mg/L, IQR)	Peak, median (mg/L, IQR)
Global cohort, n = 70 (14/56)	1.7 (1.1–3.0)	7.9 (5.3–11.2)	2.4 (1.4–4.5)	7.8 (5.9–11.2)
Intensive care unit, n = 15 (2/13)	NA *	NA *	2.7 (1.3–4.9)	7.9 (6.8–11.1)	0.336	0.267
ECMO/hemofiltration/hemodialysis, n = 15 (5/10)	1.1 (0.5–2.3)	10.6 (6.3–12.4)	3.2 (1.7–7.2)	7.9 (6.8–14.3)	0.924	0.101
HIV, n = 8 (0/8)	NA	NA	3.0 (1.5–4.8)	5.6 (3.0–7.8)	0.522	0.053
Solid organ transplant, n = 26 (9/17)	1.2 (0.9–5.3)	7.4 (5.7–12.0)	2.7 (1.3–5.0)	8.2 (4.7–12.8)	0.784	0.603

* Only 2 values. ECMO: extracorporeal membrane oxygenation. NA. Not available.