Table 3.
ANOVA for the 23 factorial design of EGCG-loaded SNVs.
| Independent Variable | Source | Sum of Squares | df | Mean Square | F-Value | p-Value |
|---|---|---|---|---|---|---|
| EE% (Y1) | Model | 497.23 | 31 | 165.74 | 25.45 | 0.0046 |
| X1 | 92.66 | 1 | 92.66 | 14.23 | 0.0196 | |
| X2 | 280.95 | 1 | 280.95 | 43.14 | 0.0028 | |
| X3 | 123.62 | 1 | 123.62 | 18.98 | 0.0121 | |
| Q12h (Y2) | Model | 1022.56 | 3 | 340.85 | 173.49 | 0.0001 |
| X1 | 49.54 | 1 | 49.54 | 25.22 | 0.0074 | |
| X2 | 898.93 | 1 | 898.93 | 457.55 | <0.0001 | |
| X3 | 74.09 | 1 | 74.09 | 37.71 | 0.0036 | |
| PS (Y3) | Model | 43,375 | 3 | 14,458 | 33.30 | 0.0027 |
| X1 | 29,598 | 1 | 29,598 | 44.67 | 0.0012 | |
| X2 | 3383.46 | 1 | 3383.5 | 14.89 | 0.0388 | |
| X3 | 10,393 | 1 | 10,393 | 40.34 | 0.0080 |
Notes: Values of p < 0.05 investigate the significance of model terms, X1: Ratio of Span to EA, X2: Type of non-ionic surfactant, X3: Type of EA. Abbreviations: EE, entrapment efficiency; Q12h, % drug released after 12 h; PS, particle size; df, degree of freedom.