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Ex vivo permeation parameters of F4, the conventional niosomes, and EGCG dispersion.
| Formula | * Jss
(µg cm−2 h−1) |
* KP
(cm h−1) |
ER |
|---|---|---|---|
| EGCG dispersion | 1.35 ± 0.11 | 0.0034 ± 0.12 | ------- |
| Niosomal formula | 6.38 ± 1.23 | 0.0119 ± 0.14 | 4.73 |
| F4 | 9.13 ± 1.34 | 0.0228 ± 0.13 | 6.76 |
Notes: * Each value represents average ± SD (n = 3), F4: the optimized EGCG-loaded SNVs. Abbreviations: Jss, the steady-state flux; KP, the permeability coefficient; ER, Enhancement ratio.
