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. 2021 Jan 18;22(2):903. doi: 10.3390/ijms22020903

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Covalent bond formation between growth factor and carrier: (A) amide group, (B) thioether group, (C) disulfide group, (D) acetyl-hydrazone group, (E) polycyclic group, and (F) click chemistry [155].