Table 1.

Phenotypes observed in dSod1 (superoxide dismutase-1) mutant backgrounds.

Mutant Line	Phenotype	Reference
dSod1n108	Homozygous lethality with rare eclosing adults, sterile, and early dying within 2–3 days No detectable superoxide dismutase activity Hypersensitivity to paraquat	[49]
	Necrotic lesions throughout retina	[50]
dSod1x16	No detectable superoxide dismutase activity	[50]
	Partially lethal	[51]
dSod1x139	No detectable superoxide dismutase activity	[50]
	Partially lethal	[51]
	Reduced eclosion rate, eclosing adults with shorter lifespan	[54,55]
dSod1x16/dSod1x139	Very reduced lifespan Impaired adult locomotion	[56]
dSod1G37R	No lethality, adult eclosion as wildtype, no adult locomotion defect.	[57]
dSod1G51S	Impaired larval crawling Reduced adult viability, adult escapers with locomotor defect	[57]
dSod1G85R	Impaired larval crawling Reduced adult viability, mostly lethal at pharate stage Adult escapers with muscle atrophy and denervation	[57]
	Reduction in NMJ bouton number and electrophysiological defect	[58]
dSod1H48R	Reduced adult viability, mostly lethal at pharate stage	[57]
dSod1H71Y	Impaired larval crawling Reduced adult viability, mostly lethal at pharate stage, adult escapers with locomotor defect, muscle atrophy, and denervation	[57]

This table describes the phenotypes associated with different dSod1 mutant lines. Note that the experiments could be done at different temperatures.