Table 2.
Clinical characteristics of 7 patients with clinically unrecognized viral sequences
Patient’s code | Age, gender | Underlying disease | GvHD organ | GvHD treatmentsa | Outcome |
---|---|---|---|---|---|
Ge02 | 61, M | Lymphoma | Digestive, skin | CSA, tacrolimus, corticosteroids, sirolimus, budenoside, photopheresis | Death (GvHD-related) |
Ge05 | 23, M | Lymphoma | Digestive, skin, lung | CSA, MMF, tacrolimus, corticosteroids | Death |
Ge07 | 60, M | ALL | Digestive | Tacrolimus, corticosteroids, photopheresis | Death |
Ge09 | 65, M | AML | Liver, digestiveb | CSA, corticosteroids, tocilizumab | Death |
Ge12 | 44, M | MM | Digestive, liver | CSA, corticosteroids, basiliximab, MMF | Death |
Ge14 | 31, M | AML | Digestive, liver | Corticosteroids | Death |
Ge22 | 68, M | MDPS | Digestive, skin | CSA, tacrolimus, corticosteroids, vedolisumab, prolastin | Death |
Age at the time of transplantation
Abbreviations: GvHD graft-versus-host disease, M male, ALL acute lymphoid leukemia, AML acute myeloid leukemia, MM multiple myeloma, MDPS myelodysplasic proliferative syndrome, CSA cyclosporine A, MMF mycophenolate mofetil
aAll patients had ruxolitinib as part of the GvHD treatment
bDigestive GvHD was not confirmed by biopsies