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. 2021 Jan 25;19:14. doi: 10.1186/s12916-020-01890-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Secular trends in the incidence rate of each indication among the general population from 2012 to 2019, by year. Gray circles: annual incidence rates of the overall CD indications; orange blocks: annual incidence rates of women with pregnancy complications; green blocks: annual incidence rates of women with tumor; blue blocks: annual incidence rates of fetal macrosomia. The annual incidence rate and its 95% CI were listed below. Annual percentage change (APC) of the incidence rates of each indications estimated by joinpoint regression models was shown