TABLE 3.
The enriched TF binding motifs of FLHS differential H3K27ac peaks.
| Rank | Name | Motif | P-value | q-value | # Target Sequences with Motif | % of Targets Sequences with Motif | Function |
| 1 | ERG |  |
1.0E-04 | 1.3E-02 | 227 | 17.18% | Angiogenesis, inflammation, and apoptosis |
| 2 | FOXA1 |  |
1.0E-04 | 1.3E-02 | 206 | 15.59% | Metabolism and glucose homeostasis |
| 3 | GABPA |  |
1.0E-04 | 2.1E-02 | 118 | 8.93% | Mitochondrial function, innate and acquired immunity |
| 4 | FLI1 |  |
1.0E-03 | 3.2E-02 | 146 | 11.05% | Development of pre-T cell lymphoblastic leukemia/lymphoma |
| 5 | ETV1 |  |
1.0E-03 | 3.2E-02 | 178 | 13.47% | Cell proliferation, apoptosis, and differentiation |
| 6 | PHA-4 |  |
1.0E-03 | 3.7E-02 | 500 | 37.85% | Excessive lipid accumulation, energy metabolism |
| 7 | ELF1 |  |
1.0E-03 | 3.7E-02 | 59 | 4.47% | Antiviral immune response |
| 8 | FOXO1 |  |
1.0E-03 | 4.5E-02 | 293 | 22.18% | Metabolism regulation, disease prevention |
| 9 | ETS1 |  |
1.0E-03 | 4.5E-02 | 145 | 10.98% | Immune homeostasis |
| 10 | ETV2 |  |
1.0E-03 | 4.7E-02 | 125 | 9.46% | Hematopoiesis and vasculogenesis |