Table 1.
Demographics, pathological analysis, and types of surgery of participants with pathologically T1a and T1b lung adenocarcinoma.
| Total (n = 190) | STAS (n = 47) | Non-STAS (n = 143) | t or z value | p | |
|---|---|---|---|---|---|
| Age (years) | 55 ± 14 | 56 ± 8 | 53 ± 11 | 1.778 | 0.100 |
| Male, n [%] | 112 [58.9] | 29 [61.7] | 83 [58] | 0.443 | 0.658 |
| Heavy smoke, n [%] | 56 [29.5] | 16 [34.0] | 37 [25.9] | 1.083 | 0.279 |
| Surgery | 1.933 | 0.05 | |||
| Sublobar resection, n [%] | 71 [37.4] | 12 [25.6] | 59 [41.3] | ||
| Lobectomy or pneumonectomy, n [%] | 119 [62.6] | 35 [74.5] | 84 [58.7] | ||
| Pathology | |||||
| Predominant histologic subtypes | |||||
| Lepidic, n [%] | 30 [15.8] | 0 | 30 [21.0] | – | 0.0001*** |
| Acinar, n [%] | 87 [45.8] | 5 [10.6] | 82 [57.3] | – | <0.0001**** |
| Papillary or micropapillary, n [%] | 38 [25.9] | 27 [57.4] | 11 [7.7] | 7.398 | <0.0001**** |
| Solid, n [%] | 26 [13.7] | 12 [25.5] | 14 [9.8] | 2.724 | 0.006** |
| Cribriform, n [%] | 9 [4.7] | 3 [6.4] | 6 [4.2] | – | 0.692 |
| Vascular invasion (+), n [%] | 26 [13.7] | 12 [25.6] | 11 [7.7] | 3.253 | 0.001** |
| Pleural invasion (+), n [%] | 31 [16.3] | 19 [40.4] | 17 [11.9] | 4.331 | <0.0001**** |
| EGFR mutation (+), n [%] | 78 [41.1] | 12 [25.5] | 66 [46.2] | 0.493 | 0.013* |
STAS, spread through air spaces; EGFR, epidermal growth factor receptor. Significant level marks: p < 0.05 *, p < 0.01 **, p < 0.001 ***, p < 0.0001 ****.